What can Gregor Mendel’s pea plants tell us about human disease ... who is most often a carrier (heterozygous) but who might be affected (homozygous). Males, on the other hand, have only ...

and premature coronary artery disease. Statins lower plasma cholesterol by upregulating LDL receptor gene expression and are consequently relatively ineffective in homozygous familial ...

BUFFALO, N.Y. — A decade ago, University at Buffalo researchers shed some light on an enduring neuroscience mystery: How exactly does a mutated huntingtin protein (HTT) cause Huntington’s disease?

The study indicates that a possible treatment for Huntington's disease would be to encourage the brain to replace lost cells with new, functional ones and restore the brain's communication pathways.

A drug originally developed for high blood pressure could find a new use in the treatment of Huntington's disease, thanks to an artificial intelligence-based drug discovery programme at Spain's ...

They found that two specific signaling proteins, GSK3ß and ERK1, were expressed more in the neurons of Huntington's disease patients, so they prevented them from functioning in the neurons of ...