These ES cells are heterozygous for the knockout mutation. Although these cells will grow and divide in culture, they cannot form an embryo that will develop into a mouse on their own. Step 4 ...

Hemann et al. crossbred telomerase-deficient mice having short telomeres with mice heterozygous for telomerase activity that have long telomeres. They found that the phenotype of the telomerase null ...

It is noteworthy that mice heterozygous for the gene encoding mGluR5 were indistinguishable from wild-type mice in regard to these phenotypes, indicating that the observed rescue is not a compound ...

with a homozygous floxed mouse (B). The offspring are heterozygous for the floxed target gene (C) and breed with the homozygous floxed mouse (B). The resulting experimental mouse is hemizygous for Cre ...

White fur is recessive - a. Grey fur is dominant - A. Two mice that are heterozygous for the fur colour gene mate. Determine the probability that the offspring will have grey fur. Because the ...