First-in-class approach enables the generation of transgene-free hematopoietic stem cells through mechanosensitive PIEZO1 ...

restricting the germ cell lineage specification during embryonic development. P-selectin has been considered as a biomarker of hematopoietic stem cell (HSC) aging. Here, Yang et al. uncovered a ...

Researchers identified 55 distinct hematopoietic cell states across the dataset ... These patterns reflected both early developmental blocks and lineage-biased differentiation toward myeloid ...

Researchers use generative AI to design synthetic enhancers that can effectively control gene expression in healthy mammalian cells.

Data presented at American Association for Cancer Research (AACR) Annual Meeting. In April 2025, Foghorn presented new preclinical data highlighting pipeline progress for potential first-in-class ...

Hematopoietic stem cells (HSCs) represent the origin of all blood cells ... and ILC progenitors (ILCPs) retain multi-lineage potential. The figure shows key transcription factors (including TCF-1, ID2 ...

In this single-arm trial, the median overall survival (OS) observed was 4.0 months (95% CI: 2.5-7.2) among all 64 adults in the primary efficacy analysis based on the Kaplan-Meier estimate. The median ...

Fritz Lipmann Institute (FLI) in Jena have discovered a previously unknown function of immune cells in the bone marrow.

Stem cells can produce any other cell type, it is just a matter of telling them in the right way. From a biological perspective, this means activating the proper genetic programme by pressing the ...

Lineage Cell (LCTX) came out with a quarterly loss of $0.02 per share in line with the Zacks Consensus Estimate. This compares to loss of $0.04 per share a year ago. These figures are adjusted for ...

Brian Culley; Chief Executive Officer, Director; Lineage Cell Therapeutics Inc Jill Howe; Chief Financial Officer; Lineage Cell Therapeutics Inc William Wood; Analyst; B. Riley Securities Jack ...