Studies have begun to show the lineage relationships between and molecular programs controlling hematopoietic cell emergence in the conceptus and the legacy of the cells emerging from distinct ...

Diverse results from many experimental systems indicate that the proliferative and self-renewal capacity of a given hematopoietic cell, as well as the diversity of lineages to which it can ...

Mapping the 1.2 million cells onto the hematopoietic reference revealed 12 recurrent patterns of differentiation across 318 patient samples. These patterns reflected both early developmental blocks ...

First-in-class approach enables the generation of transgene-free hematopoietic stem cells through mechanosensitive PIEZO1 activation Stratus has an exclusive license to the intellectual property for ...

The hematopoietic stem cells can form red blood ... stem cells as tissues contain large numbers of several types of cells. Lineage analysis is one method used to tackle this problem.

Then they mapped single-cell lineage output to gene expression against a cDNA library to generate a molecular bridge database. Lu and her team used the database to quantify HSC lineage outputs across ...

My Little Old Boy' Lee Sang-yeop revealed that he had a hematopoietic stem cell transplant for his mother.Actor Lee Sang-yeop ...

Buildup of lipid peroxides can affect critical cells called hematopoietic stem cells (HSCs ... impacted HSCs and immune cells with B cell lineage (types of white blood cells) but had few effects ...

Hematopoietic progenitor cells (HPCs) are an intermediate cell type in blood cell ... CMPs and CLPs continue to differentiate along cell lines into lineage-restricted progenitor cells that become ...

Researchers use generative AI to design synthetic enhancers that can effectively control gene expression in healthy mammalian cells.

Artificial bone marrow may be used to reproduce hematopoietic stem cells. A prototype has now been developed by scientists of KIT, the Max Planck Institute for Intelligent Systems, Stuttgart, and ...

Researchers identified 55 distinct hematopoietic cell states across the dataset ... These patterns reflected both early developmental blocks and lineage-biased differentiation toward myeloid ...