Figure 1: CRISPR–Cas systems identified in uncultivated organisms. Figure 2: ARMAN-1 CRISPR array diversity and identification of the ARMAN-1 Cas9 PAM sequence. Figure 3: CRISPR–CasX is a dual ...

This insight reveals how to tune Cas removal, contributing to future CRISPR applications. "Polarity of the CRISPR Roadblock to Transcription" published Dec. 5 in Nature Structural & Molecular Biology.

Every living creature on Earth needs to protect itself from things that would do it harm. Bacteria are no different. And ...

Scientists have categorized different types of CRISPR systems into two classes based on how their Cas nucleases function. In class 1 (types I, III, and IV), different Cas proteins form a complex ...

Researchers have uncovered a serious side effect of using the CRISPR-Cas gene scissors. A molecule designed to make the process more efficient destroys parts of the genome. Genome editing with ...

Yet others, called base editors, change one letter of the DNA code to another. So why do we call it CRISPR? Cas proteins are used by bacteria to destroy viral DNA. They add bits of viral DNA to ...

With the first medical therapy approved and systems like CRISPR-Cas showing up in complex cells, there’s a lot happening in the genome editing field. By Amber Dance/Knowable Magazine Published ...

Owen T. Tuck, a graduate student in Jennifer Doudna’s lab at the University of California. Owen T. Tuck, a graduate student in Jennifer Doudna’s lab at the University of California, Berkeley ...

This insight reveals how to tune Cas removal, contributing to future CRISPR applications. "Polarity of the CRISPR Roadblock to Transcription" published Dec. 5 in Nature Structural & Molecular Biology.