Researchers have made a breakthrough discovery that could potentially revolutionize treatments for antibiotic-resistant infections, cancer and other challenging gram-negative pathogens without relying ...

2) To phenotypically characterize multi-drug-resistant Gram-negative bacteria such as Escherichia coli, Klebsiella pneumoniae, proteus species, Citrobacter species, Salmonella and Shigella isolated ...

Using its proprietary FBDD platform, Blacksmith discovered FG-2101, the prodrug form of FG-960, the first known non-hydroxamate LpxC inhibitor that exerted activity against LpxC at the nanomolar range ...

A SYSTEMATIC review and meta-analysis suggest that a 7-day course of antibiotics is as effective as a 14-day regimen for most patients with Gram-negative bloodstream infections. Researchers conducted ...