75). Rabkinesin-6 is also localized to the Golgi complex, and may be part of a larger docking complex that uses the microtubule-based cytoskeleton to direct vesicle trafficking. Rab5 also appears ...

Laboratory of Human Genetics & Therapeutics, Smart Health Initiative, Division of Biological and Environmental Science and Engineering (BESE), King Abdullah University of Science and Technology (KAUST ...

So if a human finds, for instance, a better but more complex way to make a knife, they can pass along the new instructions. One of those learners might stumble upon their own improvement and pass ...

This important study provides solid evidence that glucosylceramide synthase (GlcT), a rate-limiting enzyme for glycosphingolipid (GSL) production, plays a role in the differentiation of intestinal ...

FZU - Institute of Physics of the Czech Academy of Sciences, 182 21 Prague, Czech Republic Faculty of Mathematics and Physics, Charles University, Ke Karlovu 3, 121 16 Prague 2, Czech Republic FZU - ...

In young organisms, it acts as a barrier against tumorigenesis, but in the aging population, it may facilitate tumor growth and metastasis through the senescence-associated secretory phenotype ...

The term "God complex" is sometimes used to describe a person who believes they are exceptional and superior to others. It is an expression and not a formal diagnosis, but some traits are similar to ...

Scientists are working across disciplines to render complex reality to scientific understanding. It has been the great triumph of the sciences to find consistent means of studying phenomena hidden by ...

While HIV-1 infection of target cells with cell-free viral particles has been largely documented, intercellular transmission through direct cell-to-cell contact may be a predominant mode of ...

Methods Whole exome sequencing (WES) was undertaken on 174 EDS patients recruited from a national diagnostic service for complex EDS and a specialist clinic for hEDS. Patients had already undergone ...

Objectives Because a significant fraction of patients with lupus nephritis (LN) develops renal impairment, there is a need to better understand the mechanisms underlying disease progression. Here, we ...