It is based on nanoparticles that mimic a special carbohydrate layer (glycocalyx) located on inflamed bowel cells, and which trigger anti-inflammatory effects in the diseased sites in the intestine.

Cancer cells often form the glycocalyx with high levels of cell-surface mucins, which are thought to help protect the cancer cell from immune cell attack. However, a physical understanding of this ...

The starting point of their approach was the glycocalyx, a carbohydrate-rich layer that coats the cells on the surface of the intestine. Beneficial gut bacteria, which have their own matching ...

In a study in aging mice, Shi has uncovered striking age-related changes in the sugary coating – called the glycocalyx – on cells that form the blood-brain barrier, a structure that protects ...

A recent study published in the journal Nature showed that the dysregulation of the brain endothelial glycocalyx layer impairs the blood-brain barrier (BBB) in disease and aging. The BBB forms a ...

One of the ways that cancer cells hide from the body’s immune system is by forming a thin surface barrier called the glycocalyx. In a new study, researchers examined the material properties of ...

This study, focused on kidney patients, reveals that the patented formulation of Endocalyx Pro restores the endothelial glycocalyx when exposed to toxic hemodialysis plasma. A healthy endothelial ...