restoring a more "youthful" glycocalyx, they improved the integrity of the blood-brain barrier, reduced neuroinflammation, and measurably improved cognitive function. "Modulating glycans has a maj ...

More information: Lara M. Hoepfner et al, Unwrapping the Ciliary Coat: High‐Resolution Structure and Function of the Ciliary Glycocalyx, Advanced Science (2025). DOI: 10.1002/advs.202413355 ...

We are currently examining the role of GEnC fenestrations and glycocalyx in glomerular barrier function in health and disease to determine potential theraputic targets. Throughout the vasculature, ...

The study focused on heparan sulfate (HS), a key component of the endothelial glycocalyx (eGC) that lines blood vessels and plays a vital role in regulating endothelial cell functions. While it is ...