The neutron data clearly show that the glutamate ... as one-carbon metabolism, this enzyme works inside a cell's mitochondria, or energy producer. It converts the amino acid serine into another ...

Glutamate and nitric oxide form a feedback loop ... Ca 2+ elevation in astrocytes that mirrored aLTP. Blocking astrocyte metabolism or depletion of the NMDA receptor ligand D-serine abolished ...

Altered metabolism of acylcarnitines ... C13:0‐carnitine), dimethylguanidino valeric acid (DMGV), cystine, and glutamate. Serine was the metabolite that predominantly had negative contributions to the ...

The enzymatic reactions necessary for de novo serine metabolism produce serine as well as antioxidants ... to 3-phosphoserine by transferring the amino group from glutamate and producing the TCA cycle ...

Animal glutamate receptor ... a pivotal role in plant metabolism and signaling. Also, L-Ser has been implicated in plant responses to both biotic and abiotic stresses. A large body of information ...

A link between macular telangiectasia type 2 and altered serine metabolism has been established previously. Through exome sequence analysis of a patient with macular telangiectasia type 2 and his ...

We consider these pathways as important processes linking carbon and nitrogen metabolism and ... 2-OG is transaminated to glutamate by aminotransferases using glycine or alanine (6), use of other ...

Major finding: mTORC2 controls glutamate and glutathione metabolism in cancer cells by phosphorylating xCT. Mechanism: Phosphorylation at serine 26 inhibits xCT activity, reducing glutamate secretion ...

We also explored if pharmacological blockade of glutamine metabolism reduced pathological ... Intracellular levels of the non‐essential amino acids glutamate, aspartate, asparagine, alanine, glycine, ...

Glu, glutamate; α‐KG ... HIFs activate the transcription of the following: genes encoding enzymes of the serine synthesis pathway (SSP) and mitochondrial one‐carbon metabolism (m1CM) to increase the ...

ABSTRACT: Background: The human serine palmitoyltransferase-1 ... Parent Glioma LN18 and SKN-SH cells and their SPTLC1 recombinants were each treated with Glutamate, an excitatory neurotransmitter ...