Excessive serine metabolism promotes abnormal macromolecule biosynthesis ... Secondly, through a transamination reaction, 3PHP receives an amino group from glutamate, producing 3-phosphoserine (3P-Ser ...

Other amino acids including aspartate, glutamate, and glycine did not change (data ... and it is known that the regulation of the enzymes responsible for serine production and metabolism has been ...

The above metabolites encompass carbohydrate, lipid, amino acid, and polyamine metabolism. Table 1 ... 5918 superpathway of heme biosynthesis from glutamate was negatively correlated with the Serine ...

Our brain requires a constant supply of energy. A disrupted energy supply, as, for instance, caused by a stroke, can have ...

A new study shows that when energy is depleted—such as during a stroke—neurons begin releasing glutamate in abnormal, self-amplifying bursts that can damage nerve cells.

Monocytes then travel to the liver and along the way become macrophages – also immune cells. The presence of glutamate reprogrammes the metabolism of macrophages, and these consequently begin to ...

Lactation triggers significant metabolic changes in mothers, driven by shifting hormone levels and brain activity.

The molecular mechanism behind why heart attacks can vary in severity depending on the time of day has been uncovered by ...

Scientists have extensively studied the role of metabolism in individual cells to understand how it influences their energetic state, but little has been studied about the effect of glycolysis on ...

Researchers at University of California, Los Angeles (UCLA) have developed a tiny sensor that can help keep tabs on metabolites – substances produced or used when your body breaks down food ...