Microglia replacement therapy helps treat people with a rare genetic condition called ALSP, suggesting the approach could ...

Would you get a one-time genetic modification such that you'd never have to take a GLP-1 drug for weight loss ever again?

Weight-loss drugs have surged in popularity, promising rapid results with regular injections. Now, researchers from Japan ...

By establishing an iron overload-induced hepatic ferroptosis model, scientists from Japan have identified iFerroptosis—an ...

By establishing an iron overload-induced hepatic ferroptosis model, scientists from Japan have identified iFerroptosis-an ...

Researchers at Shanghai Jiao Tong University have produced fertile adult mice from embryos constructed entirely with male ...

The Ca2+ stored in the cellular endoplasmic reticulum (ER) plays a crucial role in protein folding and lipid transfer, and its impairment leads to cellular ER stress. When chronic cellular ER stress ...

Many foods are often advertised for their antioxidant properties. Antioxidants counteract what are known as reactive oxygen species (ROS), chemically reactive molecules that can disrupt the normal ...

Without both doses, gene expression can go awry, and the resulting embryos can end up with abnormalities. This is what researchers have found in previous attempts to create mice with two dads.

Here, we report the genotypes and phenotypes of heteroplasmic MT-ND5 gene-knockout mice. These mutant mice presented damaged mitochondrial cristae in the cerebral cortex, hippocampal atrophy, and ...