Biologists have achieved the first gene knockout in a cephalopod using the squid Doryteuthis pealeii, an exceptionally important research organism in biology for nearly a century. The team used ...

Gene knockout: Loss of a gene can be compensated by another gene Effects of genome interventions depend on the methods used Date: July 22, 2015 Source: Max-Planck-Gesellschaft Summary: New methods ...

To do so, they cut DNA-fragments from the gene using enzymes deleting the genetic information for a functioning protein. Such method is called "Gene knockout".

Arabidopsis may seem like a simple plant, but at the University of Missouri, plant biochemist Jay Thelen is using it as a ...

The scientists specifically targeted a gene that produces ommochromes, a biological pigment which determines eye color in crustaceans and insects. By knocking out the corresponding genetic ...

Radiation therapy can promote the epidermal growth factor receptor (EGFR) ligand amphiregulin, which increases growth of ...

One of the biggest obstacles in cancer treatment is drug resistance in cancer cells. Conventional efforts have focused on ...

Therefore, by generating a knockout mouse without a gene of interest, these scientists may be able to determine the functions carried out by the related human gene.

A recently published study used the gene-editing tool CRISPR-Cas9 to disable a gene in human embryos that's critical to human development.

More than 70 genes have been linked to autism spectrum disorder (ASD), a developmental condition in which differences in the brain lead to a host of altered behaviors, including issues with ...

Most cells in the human body each contain about six feet of DNA. Yet the nucleus, where DNA is coiled, is no larger than a single speck of dust. Despite its density, DNA is not a tangled ball of yarn.

Knocking out a gene linked to brain circuitry leads to several hallmark behaviors of autism, a new study has found.