X-linked severe combined immunodeficiency disease (X-SCID) is a rare genetic disorder characterized by profound defects in ...

Codons function as instructions in the translation process, where genetic information is converted into proteins. Each codon corresponds to a specific amino acid, and the order of codons in a gene ...

A gene therapy to correct a mutation that causes maple syrup urine disease prevented newborn death and normalized growth in a calf as well as in mice.

Alltrna’s CEO Michelle Warner said that the approach allows for basket trials that can group patients with different diseases ...

X-linked severe combined immunodeficiency disease (X-SCID) is a rare genetic disorder characterized by profound defects in T-cell, B-cell, and natural ...

other groups have set out to subtly reword the genetic text — encountering an entirely different set of challenges. Such work might sound straightforward — simply substituting one codon for ...

Korro Bio, Inc. (Korro) (Nasdaq: KRRO), a clinical-stage biopharmaceutical company focused on developing a new class of genetic medicines based on editing RNA for both rare and highly prevalent ...

However, by comparing datasets of mammoth and elephant genomes, the team identified that mammoths lost the function of one of these genes. The researchers also introduced mutations into two of the ...

The team was able to reach protein yields at the pool stage that couldn’t be achieved previously with a random integration approach.

Korro Bio, Inc. (Korro) (Nasdaq: KRRO), a clinical-stage biopharmaceutical company focused on developing a new class of genetic medicines based on ...

Biopharma companies require optimal clone yields to ensure maximum concentration and effectiveness of these therapeutic ...