Cell membrane proteins hide secret gateways that can be used to modify cell behavior. This has been demonstrated in a study ...

Proteins interacting with cell membranes play a vital role in countless biological processes, from how cells communicate to ...

G-protein coupled receptors regulate hormone secretions in the pancreas. Learn how the complex signaling features of these receptors are illuminating diabetes research.

G-protein coupled receptors regulate hormone secretions in the pancreas. Learn how the complex signaling features of these receptors are illuminating diabetes research. Diabetes results from ...

Sotio Biotech is pushing deeper into bispecific antibody-drug conjugates (ADC), taking up its option to use Synaffix’s technology in two candidates. The Czech biotech disclosed the update on the same ...

Peter Hildebrand, professor of membrane and cell biophysics at Leipzig University, who led the international study, says, "Our new numbering system is an important step forward in GPCR research.

This study employed high-throughput screening and animal models to identify FPR2, a G protein-coupled receptor (GPCR) expressed at the adipocyte plasma membrane, as a critical ceramide receptor. This ...

PI3K signaling pathways. Upon activation by RTK, GPCR, Integrin, and Ras, p110 loses inhibition by p85 and converts PIP2 to PIP3. PIP3 recruits AKT to the cell membrane, where AKT is activated ...