News

Researchers reveal structural basis of prostaglandin D2 receptor DP1 activation and its implications for drug design
Recent breakthroughs in understanding the prostaglandin D2 (PGD2) receptor 1 (DP1) are paving the way for innovative ...
The European Food Information Council4d
What is a food allergy? Symptoms, causes and treatment
Discover the causes, symptoms, and treatment of food allergies, and learn how to manage them safely with expert tips on ...
C&EN6d
Fibroblast Activation Protein-Targeted Photodynamic Therapy of Cancer-Associated Fibroblasts in Murine Models for Pancreatic Ductal Adenocarcinoma
Upon activation with light of a specific wavelength ... were fed standard chow ad libitum and housed on a 12 h day–night cycle. After acclimatization for 1 week upon arrival at our institution, they ...
C&EN7d
Conditional and Reversible Activation of Class A and B G Protein-Coupled Receptors Using Tethered Pharmacology
Find more information on the Altmetric Attention Score and how the score is calculated. G protein-coupled receptors (GPCRs) transduce information encoded by external stimuli into an appropriate cell ...
News-Medical.Net9d
Advancing GPCR drug discovery with fragment screening using GCI technology
Evotec's insights into GPCRs and waveRAPID technology reveal new opportunities in drug discovery, focusing on orphan ...
PNAS25d
Cyclic peptide inhibitors function as molecular glues to stabilize Gq/11 heterotrimers
Heterotrimeric G proteins act as molecular switches that control cellular responses to external signals. Small molecules that selectively inhibit these proteins are essential for studying their ...