Recent breakthroughs in understanding the prostaglandin D2 (PGD2) receptor 1 (DP1) are paving the way for innovative ...

G-protein activation and inactivation has a basic cycle, which involves agonist binding. This is in addition to receptor activation. In turn, this induces a conformational change in such a way ...

Evotec's insights into GPCRs and waveRAPID technology reveal new opportunities in drug discovery, focusing on orphan ...

One such receptor involved in relaying molecular signals is a G protein-coupled receptor (GPCR). About one-third of existing drugs work by controlling the activation of this protein. Japanese ...

A research team led by Prof. Li Yunhai from the Institute of Genetics and Developmental Biology (IGDB) of the Chinese Academy ...