Scientists have discovered how chemokines and G protein-coupled receptors selectively bind each other to control how cells move.

Cysteinyl leukotrienes (CysLTs) are potent bronchoconstrictors, playing pivotal roles in inflammatory diseases. These lipid mediators exert their effects by activating two G protein-coupled receptors, ...

G protein-coupled receptors (GPCRs) are integral membrane proteins with seven membrane-spanning helices. Upon binding to a ligand – which can range from small molecules like cyclic AMP to ...

Scientists from St. Jude Children's Research Hospital and the Medical College of Wisconsin have created a data science framework to better understand how cells travel through the body.

GenAI offers a realistic path forward in tackling previously undruggable targets, with the potential to reshape the entire ...

In regenerative science, B7-33's potential to influence fibroblast activity and collagen turnover suggests possible implications for tissue repair and wound healing. Given that fibrosis is often a ...

Scientists from St. Jude Children's Research Hospital and the Medical College of Wisconsin have created a data science ...

April 23, 2025). Scientists from St. Jude Children's Research Hospital and the Medical College of Wisconsin have created a data ...

Structure Therapeutics Inc.’s GPCR share price has surged by 29.14%, which has investors questioning if this is right time to sell.

G protein-coupled receptors (GPCRs) are involved in many diseases, yet raising therapeutic antibodies against them is notoriously difficult because the transmembrane receptors contain only short ...

Their environments—water, lipid membranes, or other condensed phases—are critical to their function, shaping their structure ... the G-protein-coupled receptors (GPCRs), are central to how ...