In this diagram of G-protein-coupled receptor activation, the alpha, beta, and gamma subunits are shown with distinct relationships to the plasma membrane. After exchange of GDP with GTP on the ...

G beta-gamma (purple circles), and a G-protein-coupled receptor (GPCR; light green loops). Upon receptor stimulation by a ligand called an agonist, the state of the receptor changes. G alpha ...

HHMI’s Robert Lefkowitz shares prize with Brian Kobilka for research on G-protein coupled receptors. The Royal Swedish Academy of Sciences announced today that Robert J. Lefkowitz, a Howard Hughes ...