Scientists have discovered how chemokines and G protein-coupled receptors selectively bind each other to control how cells move.

G protein-coupled receptors (GPCRs) are integral membrane proteins with seven membrane-spanning helices. Upon binding to a ligand – which can range from small molecules like cyclic AMP to ...

Scientists from St. Jude Children's Research Hospital and the Medical College of Wisconsin have created a data science framework to better understand how cells travel through the body.

April 23, 2025). Scientists from St. Jude Children's Research Hospital and the Medical College of Wisconsin have created a data ...

A recent study published in Nature by a research team from the United States and China introduced a new class of engineered G-protein-coupled receptors (GPCRs) called programmable antigen-gated ...

Scientists from St. Jude Children's Research Hospital and the Medical College of Wisconsin have created a data science ...

Late-breaking oral presentation to include full Phase 1b results for TX45 in the Group 2 Pulmonary Hypertension in Heart Failure with Preserved Ejection Fraction (“PH-HFpEF”) cohortWATERTOWN, Mass., ...

G protein-coupled receptors (GPCRs) are involved in many diseases, yet raising therapeutic antibodies against them is notoriously difficult because the transmembrane receptors contain only short ...

GenAI offers a realistic path forward in tackling previously undruggable targets, with the potential to reshape the entire ...