G protein-coupled receptors (GPCRs) are integral membrane proteins with seven membrane-spanning helices. Upon binding to a ligand – which can range from small molecules like cyclic AMP to ...

G-protein coupled receptors regulate hormone secretions in ... of each of these hormones depends on specific factors. For example, beta cells secrete insulin in response to increased blood glucose ...

Scientists have discovered how chemokines and G protein-coupled receptors selectively bind each other to control how cells move.

G protein-coupled receptors (GPCRs) are involved in many diseases, yet raising therapeutic antibodies against them is notoriously difficult because the transmembrane receptors contain only short ...

Scientists from St. Jude Children's Research Hospital and the Medical College of Wisconsin have created a data science ...

The 2012 Nobel Prize for Chemistry has been awarded to Robert Lefkowitz and Brian Kobilka for groundbreaking discoveries that reveal the inner workings of G-protein-coupled receptors. Professor David ...

Adhesion G protein-coupled receptors (GPCRs ... bioinformatics and structural biology." For example, the newly developed ...