A new study in Engineering explores the role of astrocytic G protein-coupled receptors in drug addiction. It shows that these receptors, including ...

G protein-coupled receptors (GPCRs) are integral membrane proteins with seven membrane-spanning helices. Upon binding to a ligand – which can range from small molecules like cyclic AMP to ...

A new study, published today in Nature Chemistry by researchers from the University of Pittsburgh and Yale University, shows ...

A study published in Nature Chemistry by researchers from the University of Pittsburgh and Yale University shows how common ...

The proteins – large molecules that play many important roles in the body – help to relay information and are known GPCRs, or ...

This work developed a new deep learning framework, MULGONET, to predict cancer recurrence and identify key biomarkers by ...

UB Distinguished Professor creates tools for studying living cells and is developing drugs for diabetes and cancer.

These autoantibodies bind against, for example, G protein-coupled receptors like angiotensin II receptors, completely changing the endothelial surface. As part of this process, the glycocalyx is ...

These important receptors regulate numerous and diverse ... and different drugs inevitably have different qualities. For example, some companies, e.g. Altimmune (ALT) have focused on achieving ...