This study presents compelling evidence that the denitrosylase SCoR2 regulates cardioprotective metabolic reprogramming in the heart following ischemia/reperfusion injury. The findings are supported ...

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G protein–coupled receptors (GPCRs) are a protein superfamily comprising >800 members that regulate numerous cellular and physiologic responses. GPCRs represent the largest class of therapeutic ...

When we consume foods containing sugar and starch, they are converted into energy in the body's cells through a process called glycolysis.

† PharmaCenter Bonn, Pharmaceutical Institute, Pharmaceutical Chemistry I, University of Bonn, An der Immenburg 4, D-53121 Bonn, Germany ‡ Institute of Organic Chemistry, Karlsruhe Institute of ...

Departments of Medicinal Chemistry, Cardiovascular Diseases, Pharmacology, and Drug Metabolism, Merck Research Laboratories, Merck & Co., Inc., Rahway, New Jersey 07065-0900 * To whom correspondence ...

G2A is an orphan G protein-coupled receptor (GPCR), expressed predominantly in T and B cells and homologous to a small group of GPCRs of unknown function expressed in lymphoid tissues. G2A is ...