Scientists observe ribosomal cooperation that prevents pauses in protein synthesis, revealing new dynamics for cellular ...

Using electron microscopy, researchers illustrate FusB's role in antibiotic resistance, providing a molecular-level ...

The DNA is basically a book of recipes. Each recipe tells the cells in our bodies how to make specific proteins by combining ...

In an article published in Nature Communications, researchers from Uppsala Antibiotic Center, Uppsala University and ...

Scientists uncovered how the resistance protein FusB deflects fusidic acid in bacteria, using atomic-level imaging to reveal a crowbar-like resistance mechanism.

Tetracycline antibiotics impair T cell function by binding to mitochondrial ribosomes, inhibiting mitochondrial protein synthesis and oxidative phosphorylation (OXPHOS).

Researchers from the Tanenbaum group at the Hubrecht Institute have developed a new microscopy technique to observe how ribosomes function in cells. With this method, they can monitor individual ...

In addition, killing assays demonstrated that c-di-GMP inhibits ribosome assembly, thereby promoting antibiotic tolerance in E. coli. This research establishes a regulatory pathway linking c-di-GMP to ...

The main purpose of this Research Topic is to provide a comprehensive outlook of the available information on archaeal ribosomes biogenesis, structure and function. The articles will present what is ...

Contrary to expectations, ribosome binding within these complexes is not required for LARP1-mediated TOP repression or stabilization, two canonical LARP1 functions. Together, this work provides ...

Key to the new molecule’s success is its improved ability to bind to bacterial ribosomes. Many antibiotics kill bacteria by disrupting ribosomal function. However, some superbugs have evolved ...