Researchers from the National University of Singapore (NUS) have solved a 60-year-old mystery in bacterial cell envelope ...

Even after decades of research, biologists are still uncovering surprises about the human body. A team of researchers from ...

All diseases exist on a continuum, and the damage often begins early—sometimes as soon as a child is weaned off breast milk ...

New research by Sumeda Nandadasa, Ph.D., reveals how a key protein associated with Meckel-Gruber syndrome, nephronophthisis, ...

In diseases due to exposure to toxic particles like gout, macrophages elicit separate pathways for inflammation and lysosomal ...

Epithelial homeostasis is dependent on a balance between intestinal stem cell (ISC) self‐renewal, progenitor differentiation, cell shedding and apoptosis (see Fig 2 for a schematic of fly and mouse ...

Objective Interleukin (IL)-7 is mainly produced in bone marrow (BM) that forms the niche for B cells. We previously demonstrated that BM also retains pathogenic memory CD4 T cells in murine models of ...

Background To study the morphology and the density of conjunctival goblet cells (GC) in patients with Sjögren's syndrome dry eye with in vivo laser scanning confocal microscopy (LSCM), and to explore ...

Tertiary lymphoid structures (TLSs) serve as hubs for immune cell activation and coordination to generate qualitative local immune responses within tumors. However, the effect of TLSs in pancreatic ...

The functions, and thus the needs, ... The number of goblet cells in the upper 150 µm crypt was determined, and no differences were observed in any of the groups, indicating that patients who are ...

Here, the homogeneous antibodies with optimal effector functions and CAR-T cells with reverse scFv designed to target SSEA-4 could become new treatments for PDAC as demonstrated in this ...