Crown BioScience experts explore organoid models and high-content imaging to evaluate T-cell-targeted therapies and ...

These events are associated with innate training and can have long-term impacts on hematopoietic stem and progenitor cell (HSPC) development but can also compromise their function. While many ...

The cells were harvested at various time points and analyzed for signaling and activation markers by flow cytometry. T cells from WT and KO mice were ... of hnRNP L (38), and this was associated with ...

Background Autophagy has emerged as a critical homeostatic mechanism in T lymphocytes ... Setup and Tracking Beads (BD Biosciences). Flow cytometry was performed on BD Canto II or Fortessa instruments ...

This may involve a testing technology known as flow cytometry, which can measure the number and proportion of B cells, T cells, and NK cells in a sample of blood. Lymphocytosis, or a high lymphocyte ...

Group 2 innate lymphoid cells (ILC2s) play a significant role in the regulation ... mouse HS model was used and ILC2 expansion in the lungs was dynamically measured by flow cytometry. The percentages ...

Cyclin D1–CDK4/6 phosphorylates GTSE1 in cancer cells, preventing its degradation and sustaining high levels across the cell cycle, which enhances proliferation and correlates with poor prognosis.

To support physicians in treating cancer patients, oncology laboratories can benefit from adopting end-to-end automation of flow cytometry workflows ... variability in cell population frequencies ...

Phenotypic screening has re-emerged as a powerful strategy for identifying drugs based on their observable effects. Discover ...

Citation: Successful CAR-T cell therapy for end-stage multiple myeloma using advanced cellular product performed in Hong Kong (2025, March 27) retrieved 20 April 2025 from https://medicalxpress ...