Crown BioScience experts explore organoid models and high-content imaging to evaluate T-cell-targeted therapies and ...

These events are associated with innate training and can have long-term impacts on hematopoietic stem and progenitor cell (HSPC) development but can also compromise their function. While many ...

This may involve a testing technology known as flow cytometry, which can measure the number and proportion of B cells, T cells, and NK cells in a sample of blood. Lymphocytosis, or a high lymphocyte ...

Cyclin D1–CDK4/6 phosphorylates GTSE1 in cancer cells, preventing its degradation and sustaining high levels across the cell cycle, which enhances proliferation and correlates with poor prognosis.

Multi-modal data integration of single-nuclei RNA and ATAC sequencing with spatial transcriptomics, provides new molecular insights into gene regulatory networks driving cell state transitions in ...

To support physicians in treating cancer patients, oncology laboratories can benefit from adopting end-to-end automation of flow cytometry workflows ... variability in cell population frequencies ...

Phenotypic screening has re-emerged as a powerful strategy for identifying drugs based on their observable effects. Discover ...

Spatial profiling of exhausted T cells using high-plex imaging mass cytometry [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2025; Part 1 (Regular Abstracts ...

After earning a dual MD–PhD from the University of Maryland, Porter used his background in muscle cell biology to investigate heart development at Yale. It wasn’t until his move to Rochester, however, ...

Advances in cell and molecular biology have catapulted our understanding of the science of life from the basic understanding of how cells and the components of cells interact within living organisms.