The researchers show that ephrin-B2 regulates the proper spatial activation of VEGFR-2 endocytosis and signaling at the tip cell filopodia. In vitro, endothelial cells from Efnb2-knockout and ...

Filopodia are specialized structures that extend from the cell membrane to allow a cell to explore the environment around it. These thin protrusions are full of a protein called actin, which, in ...

Computer simulations of filopodia dynamics indicate that a rotating actin structure inside the tube results in friction between the membrane and the actin, leading to the spiral form that is observed.

Red cone photoreceptor cell arrangement: (Left) In wild-type retinas, red cones extend multiple filopodia toward neighboring cells, but these filopodia stop growing when they encounter other red ...

In vertebrate retinas, specialized photoreceptors responsible for color vision (cone cells) arrange themselves ... to extend thin projections called filopodia from their apical regions; however ...

AURN001 is a combination cell therapy product candidate comprised of allogeneic human corneal endothelial cells (neltependocel) and a rho kinase inhibitor (Y-27632). This investigational product ...