In contrast, Shh stimulates proliferation of Sca1-/Lrig1+ fibroblasts, which in adult skin are found throughout the papillary and reticular dermis but are particularly associated with the HFs.

Hair growth is regulated by a small cluster of hair-specific fibroblasts, the dermal papilla. But exactly how dermal papilla forms has remained elusive until now. In a recent study professor Marja ...

The papillary dermis is the more superficial of the two ... and glycoproteins. Fibroblasts are the primary cell type present in the dermis and are responsible for the production and secretion ...

The study, published online today in Developmental Cell, determined the precise mechanism by which the dermal papilla cells -- specialized signal-making fibroblasts at the bottom of each hair ...

Traditionally, fibroblasts—specialized supporting cells within the dermis—have been believed to play a key role in producing collagen. In humans, collagen is formed before and after birth.

A study in mice explains that dermal fibroblasts lose their cell identify over time and with it their capacity to produce and secrete collagen and other proteins. With age, our tissues lose their ...

Androgenetic alopecia is a common form of hair loss in both women and men. Those with androgenetic alopecia may experience regrowth of hair, but the rate of regrowth is different for everyone.

Dermal fibroblasts are key for the production of collagen and other proteins that make up the dermis and that preserve the skin's function as a barrier. The activity of these cells is also crucial ...