How did life originate? Ancient proteins may hold important clues. Every organism on Earth is made up of proteins. Although ...

DiffSMol works by analyzing the shapes of known ligands—molecules that bind to protein targets—and using ... our model to ...

Proteins are ... their biology and their structure over the past 10 years. The number of known proteases has also increased substantially and the MEROPS protease database now lists 679 known ...

In today’s digital transformation era, scientific inquiry is increasingly guided by computational tools that uncover intricate biological mechanisms. Sarika Kondra, along with co-authors Feng Chen, ...

This valuable study focuses on defining how the HSP70 chaperone system utilizes J-domain proteins to regulate the heat shock response-associated transcription factor HSF1. Using a combination of ...

Randomised controlled trials are the gold standard to assess the effectiveness and safety of clinical interventions; however, ...

The latest version of Google DeepMind and Isomorphic Labs’ AlphaFold model can predict the structure and relationships not only of proteins, but “all of life’s molecules”, according to its ...

But despite the tragedy, the family is optimistic they will be able to re-open soon. Firefighters arrived at the block of shops on Prospect Rd at around 3.30pm to black smoke billowing from the site.

A rose by any other name… is still NOT a box of chocolates! Can you imagine anyone not lusting after those luscious bites of silky sweetness? : I probably won't eat them. : Because I'm on a diet ...

C5aR2, also a GPCR, on the other hand, did not seem to signal via G proteins. Hence, C5aR2 was considered a silent receptor. But how can C5aR2, structurally similar to C5aR1, not produce the same ...