Extrachromosomal DNAs (ecDNAs) encode oncogenic driver proteins, regulatory elements, immunomodulators, and genes of yet-unknown oncogenicity (Panel A). They exist as circular pieces of DNA in the ...

This linear rule of life was thought to govern all forms of life, from humans down to bacteria ... is now using Tang's methods to look for human extrachromosomal genes produced by reverse ...

Massive extrachromosomal elements named after the hive-minded cyborg villains in Star Trek may be the first of their kind. Small circles of extrachromosomal DNA appear to be widespread in mammals, and ...

This linear rule of life was thought to govern all forms of life-;from humans down to bacteria ... is now using Tang's methods to look for human extrachromosomal genes produced by reverse ...

In contrast to chromosomal DNA, which is replicated and divvied up equally among daughter cells during cell division, the extrachromosomal DNA (ecDNA ... transcription of oncogenes, as genetic ...