Newly discovered estrogen receptor-dependent signaling pathways demonstrate that estrogen functions in the cytosol as well as in the nucleus. The classic estrogen receptor signaling pathway occurs ...

An in-depth analysis of ER+ breast cancer, focusing on its prevalence, molecular biology, current treatments, and emerging ...

PR+ breast cancer responds well to hormone therapy, underscoring the need for molecular insight and targeted treatment ...

Estrogen functions through binding of two different ... Inhibiting bone resorption via an effect on the RANK/RANKL/OPG signaling pathway (see following section); Enhancing bone formation by ...

"If we can confirm that estrogen drives nicotine seeking and consumption through olfactomedins, we can design drugs that ...

A combination, triplet therapy that targets cancer cells from within and without caused tumors to shrink or stabilize in ...

Dr. Kevin Kalinsky discusses the role of targeted therapy and clinical decision-making in managing estrogen-driven, ...

A new study led by UCLA investigators suggests that chronic stress and an unhealthy diet may work together to fuel the early ...

Stress hormones activate the β-adrenergic receptor/PKA pathway, while obesity-related ... possibly influenced by estrogen and increased β-adrenergic receptor activity, may make them more ...

and route of ET prescribed will be additive to that which is endogenously produced and will influence the hepatic synthesis of SHBG and therefore the bioavailability of the prescribed estrogen ...