After validating the linearity and the reproducibility of this method, quantitative MALDI imaging was used to study the accumulation of chlordecone in the mouse liver. Our results revealed that ...

A team of doctors from the University Clinical Center of the Republika Srpska performed procedures on two patients with liver tumors for the first time using a minimally invasive method. This is a ...

A pioneering research study published today in Cell Metabolism details how the hormone FGF21 (fibroblast growth factor 21) can reverse the effects of fatty liver disease in mice. The hormone works ...

Research shows how hormone can reverse fatty liver disease in mice. ScienceDaily . Retrieved May 30, 2025 from www.sciencedaily.com / releases / 2025 / 05 / 250514165635.htm ...

In mouse models of colorectal cancer liver metastases (CRLM), myeloid cells are immunosuppressive and inhibit activity of anti-carcinoembryonic antigen chimeric antigen receptor T (CAR-T) cells. IL-10 ...

Collectively, this study was divided into three sections. First, the related indicators of the high-fat diet combined with STZ diabetic liver injury mice were detected, including lipid accumulation, ...

Immunofluorescence image of mouse liver 72 hours after acetaminophen administration. TP53INP1 (green) marks a distinct population of cells emerging around necrotic areas. This image highlights the ...

Working toward this goal, Tomomi Aoyagi and colleagues from Kyushu University, Japan, studied the behavior of single cells in the mouse liver after acetaminophen injury and noticed that ...

Beijing Advanced Innovation Center for Food Nutrition and Human Health, Department of Applied Chemistry, China Agricultural University, Beijing 100193, P. R. China ...

Compared with controls, treated mice exhibited lower liver weight, reduced plasma alanine transaminase and aspartate transaminase levels, and decreased hepatic triglyceride and total cholesterol.

In this work, we investigated the effect of hepatocyte PPARα on non-alcoholic fatty liver disease (NAFLD). Design We constructed a novel hepatocyte-specific PPARα knockout (Pparα hep−/−) mouse model.