A study led by University of Cincinnati Cancer Center researchers sheds new light on the mechanisms by which a major oncogene ...

It is important to pay attention to morning rituals, as they not only help shape your future body, but also keep you active ...

The yeast nuclear endonuclease Rnt1 has a well-characterized role in the maturation of many ncRNA precursors. However, the scope and consequence of its function in mRNA degradation pathways is much ...

While we focus on a large-scale basis on immunisation and infectious diseases in children, the awareness about metabolic ...

Mitochondrial DNA must also be repaired after factors like oxidative stress damage it. However, around 300 different mutations in the POLG gene derail this replication-and-repair process by messing ...

Foresee Pharmaceuticals (TPEx: 6576) ("Foresee") announced today that it will actively participate in and Toby Maher, M.D., will deliver a keynote presentation titled "SyMMPonia: A Phase 2 Study of ...

POLG-related disorders can manifest at any age and present a wide range of symptoms ... single-stranded DNA-binding protein (mtSSB). TWINKLE is a mitochondrial helicase – an enzyme that unwinds the ...

Researchers present novel therapeutics that rejuvenate a previously undruggable mitochondrial regulator of aging through a new mode of enzyme activation. Leveraging a newly identified biophysical ...

Mitochondria are double membrane bound cytoplasmic organelles present in most eukaryotic cells ... These include enzymes needed for oxidative phosphorylation, and ribosomal RNA and transfer ...

including lack of enzymes essential in the energy-production process. Mitochondrial dysfunction is present in the vast majority of children and adults with autism. Given their vulnerability to ...

Present in nearly all types of human cell, mitochondria are vital to our survival ... The outer membrane also hosts a number of enzymes with a wide variety of functions. Intermembrane space ...

an antioxidant enzyme also normally found in mitochondria, to travel to the nucleus and scavenge reactive oxygen species present to prevent further damage. PRDX1 was also found to repair the damage by ...