Mitotic rounding makes sure that genetic material is evenly distributed and that the daughter cells are the same size. However, endothelial cells going through angiogenesis need to reshape ...

Aurion will operate as a separate company with full support from Alcon to advance its clinical-stage allogeneic cell therapy asset, AURN001, into Phase 3 for corneal edema secondary to corneal ...

AURN001 is a combination cell therapy product candidate comprised of allogeneic human corneal endothelial cells (neltependocel) and a rho kinase inhibitor (Y-27632). This investigational product ...

Previous research has identified cardiac pre-arterial cells ... sprouting, pre-arterial cells are primed to develop into arterial cells prior to exposure to these mechanical cues. “Now we know that it ...

In CAR T cell therapy development, antibody-coated magnetic beads enable a one-step process for cell isolation and activation, allowing clinical-scale dose production in just 2 to 3 weeks. Despite ...

First, there are visual quality concerns: FED is characterized by corneal guttata and endothelial cell dysfunction, which can compromise visual quality. Multifocal IOLs divide light into multiple ...

provide evidence suggesting that the p130Cas drives the formation of condensates that sprout from focal adhesions to cytoplasm ... (A & B) Fluorescence image of GFP-trap magnetic beads incubated with ...

CRP kinetics to predict long-term efficacy of first-line immune-checkpoint inhibition combination therapies in metastatic renal cell carcinoma: An updated multicenter real-world experience applying ...

The retrospective comparative analysis looked at the safety and efficacy of injectable human endothelial cell therapy in patients with corneal edema in clinical trials conducted in Japan and El ...

Monomers are arranged head to tail, forming a beads-on ... 1 with tip cells also occurred at angiogenic sites in other tissues. Immunostaining of mouse brain sections localized fibrillin-1 and MAGP1 ...

Endothelial cells have been relatively overlooked in most studies of single-cell gene expression in the brain. Now, researchers led by Rachel Bennett at Massachusetts General Hospital, Charlestown, ...