Only you know when it is time' Ellen DeGeneres speaks out about ending her daytime talk show: 'My instinct told me it's time' ...

"I live with that regret," she said. "If someone in your life has the courage to speak out, please believe them." Ellen DeGeneres first revealed in 2018 that she was sexually assaulted as a teenager.

For more on Ellen DeGeneres and Portia de Rossi, pick up the latest issue of PEOPLE, on newsstands Friday, or subscribe here. Having ridden out the pandemic ... also hosts her Game of Games ...