Relevance section written by JCO Associate Editor Thomas E. Stinchcombe, MD. The promising data from the ... CONSORT diagram (patient disposition). HER3, human epidermal growth factor receptor 3; PD, ...

has been observed to emerge in long-term evolution experiments of E. coli in continuous culture. Here, we describe a computational method to model and systematically identify synergistic strains that ...

In this work, a cybernetic model was developed to represent the growth of two E. coli strains (JM 109 and BL 21 -DE3-) on a medium containing glucose and glycerol as carbon and energy sources. The ...