Researchers have identified two new drug families that block a key tuberculosis (TB) enzyme, offering hope for novel ...

A promising path to fighting COVID and other coronaviruses may have been based on a serious mistake. Scientists had zeroed in ...

EM, researchers elucidated the structure of key receptors integral to fast excitatory synaptic transmission in the rat ...

Every protein in the body is encased in a water shell that directs protein structure, provides vital stability and steers ...

Structure verification by NMR is a vital task in drug discovery but can be slow and subjective. This article explores how ASV ...

Scientists have studied a new target for antibiotics in the greatest detail yet—in the fight against antibiotic resistance.

Scientists have mapped the molecular structure of glutamate receptors in the cerebellum for the first time using ...

While biopharmaceutical technologies have made substantial strides in treating diseases, drug research and development ...

Scientists have discovered how to turn molecules made by everyday toxic mold into highly effective cancer-fighting drugs.

China’s National Medical Products Administration (NMPA) has approved four new drugs developed by local biopharma companies, ...

Here we use cryogenic electron microscopy to determine the structure of TbAQP2 from Trypanosoma brucei, bound to either the substrate glycerol or to the sleeping sickness drugs, pentamidine or ...

XtalPi has accrued a number of Big Pharma partners over the years, including Eli Lilly, which struck a $250 million deal in 2023 to use XtalPi’s tech to identify potential drug candidates that Lilly ...