A promising path to fighting COVID and other coronaviruses may have been based on a serious mistake. Scientists had zeroed in ...

Structure verification by NMR is a vital task in drug discovery but can be slow and subjective. This article explores how ASV ...

While biopharmaceutical technologies have made substantial strides in treating diseases, drug research and development ...

Every protein in the body is encased in a water shell that directs protein structure, provides vital stability and steers ...

Molecular architecture of M. tuberculosis MmpL4. Credit: Nature Communications (2025). DOI: 10.1038/s41467-025-56888-6 ...

Here we use cryogenic electron microscopy to determine the structure of TbAQP2 from Trypanosoma brucei, bound to either the substrate glycerol or to the sleeping sickness drugs, pentamidine or ...

Scientists have mapped the molecular structure of glutamate receptors in the cerebellum for the first time using ...

XtalPi has accrued a number of Big Pharma partners over the years, including Eli Lilly, which struck a $250 million deal in 2023 to use XtalPi’s tech to identify potential drug candidates that Lilly ...

SandboxAQ releases over 5 million AI-generated protein-drug structures to accelerate drug discovery and rival lab testing.

EM, researchers elucidated the structure of key receptors integral to fast excitatory synaptic transmission in the rat ...

A new cancer drug candidate developed by Lawrence Livermore National Laboratory, BridgeBio Oncology Therapeutics and ...

The model’s predecessor, Boltz-1, was released last November as the first fully open-source model to achieve AlphaFold 3-level accuracy in predicting the 3D structure of biomolecular complexes ...