As of the January 10, 2025 data cutoff, 52 patients with advanced solid tumors were enrolled to the dose escalation portion of the trial across dose levels ranging from 50 mg to 800 mg.

Phase I dose escalation study of the first-in-class selective PTEFb inhibitor BAY 1251152 in patients with advanced cancer: Novel target validation and early evidence of clinical activity. This is an ...

In our study, we do not find evidence that CBFAML is selectively responsive to high-dose cytarabine. In fact, we did not see a therapeutic benefit of cytarabine escalation above 1000 mg per square ...

Repeated positive recommendation from Data Safety Monitoring Board ("DSMB") of pivotal Phase 3 study for lead clinical ...

The European Society for Medical Oncology (ESMO) is pleased to announce the publication of the latest version of the scale that measures the clinical benefit of cancer treatments, the ESMO-MCBS ...

Armata Pharmaceuticals ARMP shares have skyrocketed 72.3% in the past month. The massive surge in the stock price was ...

In acute coronary syndrome (ACS), a prasugrel (Effient)-based antiplatelet regimen passed muster for reducing bleeding ...

Conclusions Dose escalation with escitalopram above 20 mg may have a useful role in the management of patients with MDD, although further studies are needed to confirm this finding.

Preconditioning with lymphodepletion linked to stronger MAR-T cells response and suggests enhanced anti-tumor activity Highest enrollment since study launch underscores momentum and signals a positive ...

One additional factor may have been that the patient’s lower lean muscle mass of 45% resulted in his receiving a relatively higher vector dose per muscle nucleus than patients in other studies ...

Asian markets have been buoyed by the recent de-escalation in U.S.-China trade tensions, which has injected a dose of optimism into regional equities. Amid this positive backdrop, dividend stocks in ...

Dopamine is an inotropic agent that has vasodilatory effects at low doses. It is a common belief that low-dose dopamine may be helpful in the prevention and treatment of acute renal failure and is ...