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In the video above she explains just how her theory and process of “directed evolution” works – and what problems her research could help solve.
In the directed evolution of proteins, vast numbers of slightly altered variants of a starting protein are produced. This creates a large pool of potential candidates for later use in biomedical ...
Directed evolution optimizes protein function by the successive generations of random mutation, artificial selection or screening. This simple design algorithm circumvents our ignorance of how ...
The team now reports using directed evolution, an iterative process of protein mutation and screening for activity, to identify amino acid substitutions that convert an enzyme into a predominantly ...
Instead, they may resort to directed evolution, that is, a human-directed version of the biology’s most powerful process. The pioneers of directed evolution recognized by the Nobel committee ...
Directed evolution is essentially what happens when humans take the reins. By deliberately controlling the environmental pressures on microbes, scientists can guide them to evolve certain traits ...
The California Institute of Technology (Caltech) team, and collaborators, used directed evolution to engineer a bacterial cytochrome P450 variant that could break silicon-carbon bonds in both ...
Directed evolution—a process in which a protein library is subjected to repeated rounds of mutation and selection to achieve desired properties—can improve the catalytic performance of ...
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