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Chronic wounds in diabetes can take months to heal. In a diabetes mouse model, this new gel led to a 90% wound closure rate in just 12 days.
In a new Scientific Reports study, curcumin protected bone-forming cells from high-glucose damage by activating the ...
Scientists have created a novel, long-lasting "smart" insulin that self-activates when blood sugar soars. Tests on mouse models for type 1 diabetes show that one injection works for a minimum of 14 ...
The researchers used a unique heparanase inhibitor, OVZ/HS-1638, to therapeutically target the glycocalyx in type 2 diabetic mouse models.
New research from the Charles Perkins Center at the University of Sydney has uncovered a new biological pathway that may help ...
They found that the SCAN enzyme was essential for normal insulin action, but also discovered heightened SCAN activity in diabetic patients and mice with diabetes. Mouse models without the SCAN enzyme ...
The present study used a widely recognized type 1 diabetes mouse model, the non-obese diabetic or NOD mice, to understand the impaired hypoglycemia-induced secretion of glucagon in type 1 diabetes.
Treating pre-diabetic mice resulted in a lower rate of diabetes development from 58% to 18%. This research in mice is a key first step in the development of treatments for human patients.
Using MALDI mass spectrometry imaging (MALDI-MSI), the team profiled metabolic changes in diabetic mouse kidneys and found eight spatially distinct metabolites linked to DN severity (Figure 1).
For their experiments, the team used a diabetic mouse model that exhibits impaired wound healing. They made wounds measuring about eight millimeters in diameter on the back skin of these mice and ...