The results show that Foxn1 not only plays a crucial role in development of the thymus in the embryo, but it also regulates vital functions in the developed, postnatal organ. Researchers at the ...

Figure 1: A model of the early stages of T-cell development in the thymus. Figure 2: A model of the transitional stages that are associated with β-selection.

Despite its importance, little is known about the early development of the thymus, as it uniquely functions primarily during infancy and then gradually degenerates over the lifespan. Studying its ...

Thymic organogenesis is governed by the highly potent Tecs produced during early fetal development. The thymus is a critical organ of the immune system and helps the body fight against several ...

Since the thymus is so important for immune system development during childhood, a thymectomy during childhood (before puberty) can also lead to issues. When this happens, people may have lower T ...

The development of a transplantable and scalable artificial thymus organoid could position FibroBiologics as a leader in immunotherapy and chronic disease treatment, showcasing the company's ...

The thymus is one of the most important organs ... and function is necessary and could serve to further the development of cell-based therapies for thymic defects,” senior author Holger Russ ...

1 However, in that same year, Jacques Miller discovered that the thymus “regulates lymphocyte production” and thus plays a “very important part in the development of immunological response.” ...

HOUSTON, April 29, 2025 (GLOBE NEWSWIRE) -- FibroBiologics, Inc. (Nasdaq: FBLG) (“FibroBiologics”), a clinical-stage biotechnology company with 240+ patents issued and pending with a focus on ...

It has been long known that this small organ is important for immune defense development in children. After puberty, the thymus decreases in size and is eventually replaced by fat, in a process ...

The thymus gland is part of our lymphatic system. It’s involved in the development of a type of white blood cell called a T lymphocyte. These white blood cells are part of your immune system. They ...