Within this laboratory, the "Cytoskeleton and Cancer Progression" research group, led by Dr. Clément Thomas, focuses in particular on the actin cytoskeleton and related signaling pathways in the ...

Disorganization of the actin cytoskeleton induces alterations of intestinal barrier functions, leading to passage of fluids into the intestinal lumen, but to a lesser degree. Intracellularly ...

The actin cytoskeleton provides force for dynamic cellular processes, such as motility, morphogenesis, cell division, endocytosis, and phagocytosis. The organization and dynamics of actin filaments ...

In turn, the cytoskeleton relies on a type of actin protein, called filamentous or F-actin. It forms networks of thin, flexible filaments that affect the shape, stiffness, and movement of cells.

The actin cytoskeleton is a dynamic network made up of actin polymers and associated actin binding proteins. The actin cytoskeleton was originally isolated as a component of the actomyosin complex ...

We aim to understand the molecular logic behind the dynamics of the actin cytoskeleton at endocytic sites and how disturbances in this process affect physiology and disease progression. Leonardo is ...

The new research findings show that filamentous actin, a component of the cytoskeleton, interacts with the androgen receptor directly in the cell nucleus and strengthens its effect. The androgen ...

which provide key structural support as part of the cell "cytoskeleton," the system that gives cells their shape and polarity. Rapid changes in actin filaments underlie key cellular events such as ...