REVEAL-1 Cohort 3-month open-label data update expected in June 2025; early clinical signals reinforce Revita's potential to maintain weight loss after GLP-1 discontinuation in the real world REMAIN-1 ...

The New York Jets have selected former FSU cornerback Azareye'h Thomas with the 73rd overall pick in the third round of the 2025 NFL Draft. Thomas just completed his third season in Tallahassee ...

In the experimental diabetic model, db/db male mice and non-diabetic control male mice (db/+) were subjected to caffeine or vehicle eye drops. Caffeine or vehicle eye drops were administered to ...

After a week of adaptive feeding, the diabetic model was established with an RBG level of more than 16.7 mmol/L. Then, the db/db mice were randomly allocated to four groups (n = 10 per group): 1) ...

Next, we examined whether fenofibrate alleviated renal fibrosis in diabetic mice. Sirius red staining and Masson's staining exhibited that renal fibrosis was promoted in db/db group compared to db/m ...

Strikingly, addition of SRI-37330 to the drinking water of obese diabetic db/db mice, a model of severe Type 2 diabetes, led within days to normalization of their blood glucose. Similarly, SRI-37330 ...

Conclusions: Systemic inhibition of exosome synthesis/formation by GW increased ischemic limb repair in diabetic db/db mice, at least partially, via histone methylation mediated suppression of HGF.

The scientific team also demonstrated the therapeutic effects by experimenting on diabetic (db/db) mice. Treatment began by applying the device near the abdomen of the db mouse. Microneedles ...

We hypothesized that Smad3 may play a key role in the pathogenesis of cardiovascular remodeling associated with diabetes mellitus and obesity. We generated leptin-resistant db/db Smad3 null mice and ...

Talchai and colleagues then described evidence of beta-cell dedifferentiation and loss of Foxo1 activity in two other mouse models of type 2 diabetes (leptin-receptor–deficient db/db mice and ...