About Dordaviprone Dordaviprone (ONC201) is a novel first-in-class small molecule imipridone that selectively targets the mitochondrial protease ClpP and dopamine receptor D2 (DRD2). Dordaviprone ...

Recently, a new class of therapeutics that disable the neonatal Fc receptor (FcRn), which protects IgG from degradation, has emerged to treat IgG-mediated autoimmune disease. 4,5 Here, we review ...

Get Instant Summarized Text (Gist) A 2016 bird flu variant was found to be one mutation away from binding to human receptors, highlighting the potential for avian influenza to adapt to humans. The ...

Proportion of adult managed care organizations with availability varied from 24 to 100 percent for SGLT2 inhibitors, 0 to 99 percent for GLP-1 receptor agonists. (HealthDay News) — Many Medicaid ...

- Addition of dordaviprone strengthens Jazz's late-stage oncology pipeline and reinforces commitment to addressing rare diseases with significant unmet need - DUBLIN, April 21, 2025 /PRNewswire ...

Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) are a group of drugs used to treat type 2 diabetes and sometimes obesity. GLP-1 RAs are very effective at lowering blood sugar levels.

They work by activating the glucagon-like peptide 1 receptor (GLP-1R) to stimulate insulin secretion, which makes one feel fuller for longer. 1 “[The study] just really goes to show that the adipose ...

These receptors are found throughout your body. Endocannabinoids bind to them in order to signal that the ECS needs to take action. There are two main endocannabinoid receptors: CB1 receptors ...

It acts on more than 65 receptors in your brain, some of which affect your levels of serotonin. That’s a brain chemical that helps control your mood. Several drugs already used to treat anxiety ...

Many in the medical community believe there’s clear evidence that a fetus – a developing baby in the womb – can’t feel physical pain until after the 24th week (6th month) of pregnancy. But ...