Cohesin is a protein that forms a ring-shaped complex which wraps and alters the DNA molecule shape. It moves through the DNA ...

Cohesin is a protein that forms a ring-shaped complex which wraps and alters the DNA molecule shape. It moves through the DNA ...

The authors created a useful collection of Rep protein variants with changes that alter the amino acid sequence, but these did not lead to clear improvements in how the virus worked. Instead, their ...

This landmark study describes the structure of the human RAD51 filament with a recombination intermediate called the displacement loop (D-loop). Using cryogenic structural, biochemical, and ...

If DNA bridges remain between chromosomes after cell division, chromosomes become improperly segregated, resulting in genetic ...

Abstract Faithful chromosome segregation requires the removal of all DNA bridges physically linking chromatids before the completion of cell division ...

This study proposes a new mechanism by which Chd1 senses and responds to DNA unwrapping via EDBL engagement to suppress ...

PAX3 is a transcription factor (proteins involved in converting DNA into RNA) that drives melanoma progression by promoting ...

PAX3 is a transcription factor (proteins involved in converting DNA into RNA) that drives melanoma progression by promoting ...

If DNA bridges persist between chromosomes during cell division, chromosomes are abnormally segregated, leading to genetic ...

Efforts that began in the late 1990s established that a transmembrane receptor for DNA called toll-like receptor 9 (TLR9) acts in cells to initiate inflammatory responses after binding to engulfed ...