We often take facts we learn — like the fact that transcription factors bind to DNA — for granted. Or maybe not. See how researchers used DNA footprinting and gel shift assays to prove this idea.

Sequence motifs are short, recurring patterns in DNA that are presumed to have ... and gel-shift or reporter construct assays, whereas binding affinities to artificial sequences were explored ...

Ninning Liu, a bioengineer at the Wyss Institute at Harvard University, elucidated the use of DNA barcodes in high-throughput assays to determine the expression of genes in a single cell. “The goal of ...

To do so, they planned to stabilize proteins at their chromatin binding locations and use nucleic ... Following reversal of the crosslinks, they analyzed the DNA fragments using a dot blot ...

The research-use-only assay, which includes a qPCR detection kit and an isolation kit for cell-free DNA and exosomal RNA ... was designed to detect 11 ESR1 ligand-binding domain mutations in ...