Ring-shaped extrachromosomal DNA is implicated in many cancers. Rachel Brazil talks to the scientists trying to uncover their ...

For the first time, scientists have identified promising drug candidates that bind irreversibly with a notoriously ...

Scientists have identified promising drug candidates that bind irreversibly with a notoriously “undruggable” cancer protein ...

For the first time scientists have identified promising drug candidates that bind irreversibly with a notoriously "undruggable" cancer protein target, permanently blocking it.

Using an unbiased approach, this important study discovered a role of Ezh2 in the differentiation of granule neuron precursors, the cell of origin for Shh group of medulloblastoma. Furthermore, the ...

For the first time, scientists have witnessed the very moment DNA begins to unravel, revealing a necessary molecular event ...

In this article, we discuss transformation, bacterial transformation in particular, and how scientists can utilize it to ...

Alternative splicing (AS) of pre-mRNA plays a crucial role in tissue-specific gene regulation, with disease implications due to splicing defects. Predicting and manipulating AS can therefore uncover ...

Scientists have finally captured footage of the microscopic machinery that allows our cells to copy DNA—a fundamental process ...