News

From sequence to structure: A fast track for RNA modeling
In Biology 101, we learn that RNA is a single, ribbon-like strand of base pairs that is copied from our DNA and then read ...
'Selfish' genes called introners proven to be a major source of genetic complexity
DNA is the genetic code that provides the biological instructions for every living species, but not every bit of DNA helps ...
Quanta Magazine3mon
The Poetry Fan Who Taught an LLM to Read and Write DNA
It uses those patterns to predict how changes to DNA affect the function of its downstream products, RNA and proteins. The LLM has also written new sequences for alternative versions of molecules; in ...
GEN2y
DNA Changes that Don’t Change Protein, Still Affect Function in Time
A change in the DNA sequence of a codon may not change the corresponding amino acid residue in the encoded protein because each residue can be encoded by several codons. This is called the Wobble ...
Hosted on MSN4mon
1st-of-its-kind database reveals how DNA mutations 'destabilize' proteins, triggering genetic disease
"Missense" mutations — changes in a DNA sequence that swap one amino acid for another — in nearly 5,000 human proteins are known to cause genetic diseases, such as Huntington's disease and ...
The New England Journal of Medicine1y
A Holy Grail — The Prediction of Protein Structure
This year’s Lasker Basic Medical Research Award recognizes the contributions of Demis Hassabis and John Jumper for their invention of the AlphaFold artificial intelligence (AI) system, which ...